Glycosaminoglycans in Scleroderma and Scleredema

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Scleredema of Buschke.

Main text A 46-year-old African-American male with a history of type-1 diabetes (DM) was referred to the Rheumatology clinic for a further evaluation of possible systemic scleroderma. He reported a 3-year history of skin thickening and hyperpigmentation on his back and shoulders. Over the last 12 months, his symptoms progressed, involving the proximal arms, legs, and back with sparing of his ha...

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Juvenile scleredema of Buschke.

AIM To recognize a line of treatment for scleredema of Buschke in an adolescent. BACKGROUND Scleredema of Buschke is an uncommon disorder characterized by induration of the skin, which includes a non pitting hardening of the skin around the neck, shoulders, and trunk sometimes the face. Three variants are recognized. The histopathologic features of scleredema are characterized by thickened co...

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Scleredema associated with Sjögren’s syndrome*

Scleredema adultorum of Buschke is a rare disorder characterized by diffuse swelling and non-pitting induration of the skin usually involving the face, neck, arms and upper trunk. It has been associated with previous infectious diseases, diabetes, paraproteinemia and, more rarely, malignant neoplasms or autoimmune disorders. We report the case of a 30-year-old man who presented with a 2-year hi...

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Electron beam therapy in patients with scleredema.

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 1972

ISSN: 0022-202X

DOI: 10.1111/1523-1747.ep12538919